博士、研究员、博导、研究组长、学科带头人

教授，医学博士，哲学学士，国家精神疾病医学中心、上海交通大学医学院附属精神卫生中心（上海市精神卫生中心）研究员，博士生导师。现任上海市重性精神病重点实验室执行主任，精神疾病样本库主任，上海交通大学Bio-X研究院特聘教授、转化医学研究院兼职教授，国家重点研发精准医学项目首席科学家，上海交通大学冥想高阶指导师项目创始人。中国神经科学学会精神病基础与临床分会（CSNP）常委、CSNP神经调控联盟主席、上海医师协会整合医学学分会副会长、上海交通大学女医师女教师协会会长、上海市欧美同学会妇女委员会副主任、上海市三八红旗手、上海市浦江人才。《General Psychiatry》等刊物编委。。

研究方向：精神疾病精准医学、冥想机制及应用、基于精准医学的非药物整合干预治疗精神疾病

研究成果：

 近年来开创了基于精准医学检测的非药物整合干预治疗精神疾病的方向。主持国家自然科学基金（5项）、国家重点研发精准医学项目等多项科研项目。在国内首次采用基因芯片筛查精神分裂症易感基因，在国际上发现数个新的精神疾病风险基因及生物标记物，在《Journal of Clinical Investigation》、《Brain》、《Molecular Psychiatry》、《eBiomedicine》等高影响力刊物上发表论文90余篇。授权发明专利多项，主编、参编多部学术专著，主编我国首部从科学角度系统介绍冥想的《冥想科学基础与应用》及国内首部《精神分裂症精准医学临床诊疗指南》《双相障碍精准医学临床诊疗指南》《精神疾病啮齿类动物模型及行为学实验》等专著。

联系方式：
地址：上海市沪闵路3210号科研楼
Email: manyucc@126.com

Donghong Cui:  MD& PhD.

Professor of psychiatry of Shanghai Jiao Tong University School of Medicine and Principal Investigator of the Shanghai Mental Health Center. Shi is the executive director of Shanghai Key Laboratory of Psychotic Disorders, and director of Bio-Bank of mental illness.  She received her Ph.D. from Fudan University, Shanghai. She pursued postdoctoral training in Yale University, USA. She serves as the Standing Committee Member and secretary general of the Chinese Society of Neuroscience& Psychiatry (CSNP), the President of the neuromodulation Union of CSNP, the Standing Committee Member Chinese Research Hospital Association Clinical Data and Biobank Committee; the Executive Committee Member of the Shanghai Society of Genetics, and the Committee Member of China Medicinal Biotech Association Biobank Branch, etc.
Her research has been supported by grants from NSFC, Ministry of Science and Technology of the People’s Republic of China, and Science and Technology Commission Shanghai Municipality etc. She is the PI of National Key R&D Program of China “The multimodal precise medicine on diagnosis and treatment for schizophrenia and biphasic disorder”.
Her research interests focus on Pathogenesis of Schizophrenia, bipolar disorder and other Psychotic disorders; biomarkers and precision medicine of psychotic disorders; Mechanism of metabolic disorders induced by antipsychotic drugs ; Identification of features of speech for diagnosis of manic psychosis. In recent years she also explore mechanism of meditation to promote psychosomatic health
Dr. Cui won several awards, and more than 70 academic papers have been published in journals such as <Molecular Psychiatry>, <Journal of Clinical Investigation> , etc.

代表性论文：

• Xue, T., Liu, W., Wang, L., Shi, Y., Hu, Y., Yang, J., Li, G., Huang, H., & Cui, D*. (2023). Extracellular vesicle biomarkers for complement dysfunction in schizophrenia. Brain : a journal of neurology, awad341. Advance online publication. https://doi.org/10.1093/brain/awad341
• Xing, M., Gao, H., Yao, L., Wang, L., Zhang, C., Zhu, L., & Cui, D*. (2023). Profiles and diagnostic value of intestinal microbiota in schizophrenia patients with metabolic syndrome. Frontiers in endocrinology, 14, 1190954. https://doi.org/10.3389/fendo.2023.1190954
• Sun, Y., Ju, P., Xue, T., Ali, U., Cui, D.*, & Chen, J. (2023). Alteration of faecal microbiota balance related to long-term deep meditation. General psychiatry, 36(1), e100893. https://doi.org/10.1136/gpsych-2022-100893
• Huang, Y., Cui, D., Chen, L., Tong, H., Wu, H., Muller, G. K., Qi, Y., Wang, S., Xu, J., Gao, X., Fifield, K. E., Wang, L., Xia, Z., Vanderluit, J. L., Liu, S., Leng, L., Sun, G., McGuire, J., Young, L. H., Bucala, R., … Qi, D. (2023). A pref-1-controlled non-inflammatory mechanism of insulin resistance. iScience, 26(6), 106923. https://doi.org/10.1016/j.isci.2023.106923
• Xue, T., Chiao, B., Xu, T., Li, H., Shi, K., Cheng, Y., Shi, Y., Guo, X., Tong, S., Guo, M., Chew, S. H., Ebstein, R. P., & Cui, D*. (2022). The heart-brain axis: A proteomics study of meditation on the cardiovascular system of Tibetan Monks. EBioMedicine, 80, 104026. https://doi.org/10.1016/j.ebiom.2022.104026
• Zheng, J., Suo, L., Zhou, Y., Jia, L., Li, J., Kuang, Y., Cui, D., Zhang, X., & Wu, Q. (2022). Pyk2 suppresses contextual fear memory in an autophosphorylation-independent manner. Journal of molecular cell biology, 13(11), 808–821. https://doi.org/10.1093/jmcb/mjab057
• Xue, T., Wang, X., Hu, Y., Cheng, Y., Li, H., Shi, Y., Wang, L., Yin, D., & Cui, D*. (2022). Embryonic Deletion of TXNIP in GABAergic Neurons Enhanced Oxidative Stress in PV+ Interneurons in Primary Somatosensory Cortex of Aging Mice: Relevance to Schizophrenia. Brain sciences, 12(10), 1395. https://doi.org/10.3390/brainsci12101395
• Xing M, Sheng J, Cui M, Su Y, Zhang C, Chen X, Fang Y, Cui D*, Li Z*. Differing prevalence and correlates of metabolic syndromes between chlorpromazine and clozapine: a 10-year retrospective study of a male Chinese cohort.Curr Neuropharmacol. 2022 Mar 2. doi: 10.2174/1570159X20666220302153123. Online ahead of print.
• Chen X, Chen Y, Qi D, Cui D*.Multifaceted interconnections between macrophage migration inhibitory factor and psychiatric disorders.Prog Neuropsychopharmacol Biol Psychiatry. 2022 Jan 10;112:110422. doi: 10.1016/j.pnpbp.2021.110422.
• Guo X, Wang M, Wang X, Guo M, Xue T, Wang Z, Li H, Xu T, He B*, Cui D*, Tong S*. Progressive Increase of High-Frequency EEG Oscillations during Meditation is Associated with its Trait Effects on Heart Rate and Proteomics: A Study on the Tibetan Buddhist. Cereb Cortex. 2021 Dec 31:bhab453. doi: 10.1093/cercor/bhab453. Online ahead of print.
• Wang X, Hu Y, Liu W, Ma Y, Chen X, Xue T, Cui D*.Molecular Basis of GABA Hypofunction in Adolescent Schizophrenia-Like Animals.Neural Plast. 2021 Apr 15;2021:9983438.
• Zhang Y, Cui D*.Evolving Models and Tools for Microglial Studies in the Central Nervous System.Neurosci Bull. 2021 Aug;37(8):1218-1233.
• Su Y, Yang L, Li Z*, Wang W, Xing M, Fang Y, Cheng Y, Lin GN, Cui D*.The interaction of ASAH1 and NGF gene involving in neurotrophin signaling pathway contributes to schizophrenia susceptibility and psychopathology.Prog Neuropsychopharmacol Biol Psychiatry. 2021 Jan 10;104:110015.
• Liu W, Fang Y, Shi Y, Cheng Y, Sun C*, Cui D*.The interaction of histone modification related H3F3B and NSD2 genes increases the susceptibility to schizophrenia in a Chinese population.Prog Neuropsychopharmacol Biol Psychiatry. 2020 Jul 13;101:109918.
• Shen H, Chen M, Cui D*.Gen Psychiatr. Biological mechanism study of meditation and its application in mental disorders.2020 Jul 13;33(4):e100214. [8]
• Guan Ning Lin, Sijia Gu , Jingru Wang , Shunying Yu , Zhen Wang , Donghong Cui* , Han Wang *.PsyMuKB: An Integrative De Novo Variant Knowledge Base for Developmental Disorders. Genomics Proteomics Bioinformatics.17 (4), 453-464 ,Aug 2019
• Yu Fang, Weidi Wang, Cuizhen Zhu , Guan Ning Lin, Ying Cheng , Junhui Zou*, Donghong Cui*. Use of tobacco in schizophrenia: A double‐edged sword. Brain Behav. 2019 Nov;9(11):e01433. doi: 10.1002/brb3.1433.
• Jiang H, He B*, Guo X, Wang X, Guo M, Wang Z, Xue T, Li H, Xu T, Ye S, Suma D, Tong S*, Cui D*..Brain–Heart Interactions Underlying TraditionalTibetan Buddhist Meditation.Cereb Cortex.2020 Mar 21;30(2):439-450. doi: 10.1093/cercor/bhz095
• Zhou W, Xu Y, Lv Q, Sheng YH, Chen L, Li M, Shen L, Huai C, Yi Z*, Cui D*, Qin S*.Genetic Association of Olanzapine Treatment Response in Han Chinese Schizophrenia Patients. Front Pharmacol. 2019 Mar 4;10:177.
• Cui D*, Peng Y, Xu Y, Qi D, Bucala R.Macrophage migrationinhibitory factor mediates metabolic dysfunction induced by atypicalantipsychotic therapy.JClin Invest.2018 Nov1;128(11):4997-5007.
• ShengJL,Yuan TF, Cui DH*. Theeffects of Mindfulness Meditation on hallucination and delusion in severeschizophrenia patients with more than 20 years‘ medical history. CNS NeurosciTher. 2018 Sep 28.
• LinY, Peng Y, Zhou R, Cui D*.SerumIL-1ra, a novel biomarker predicting olanzapine-induced hypercholesterolemiaand hyperleptinemia in schizophrenia.ProgNeuropsychopharmacol Biol Psychiatry.2018 Jun 8;84(Pt A):71-78.
• ZhangJ, Pan Z, Gui C, Cui D*.Analysis on speech signal features ofmanic patients.J Psychiatr Res.2018 Mar;98:59-63.