博士、研究员、研究组长、博士生导师

教授，医学博士，哲学学士，国家精神疾病医学中心、上海交通大学医学院附属精神卫生中心（上海市精神卫生中心）研究员，博士生导师。现任上海市重性精神病重点实验室执行主任，精神疾病样本库主任，上海交通大学Bio-X研究院特聘教授、转化医学研究院兼职教授，国家重点研发精准医学项目首席科学家，上海交通大学冥想高阶指导师项目创始人。中国神经科学学会精神病基础与临床分会（CSNP）常委、CSNP神经调控联盟主席、上海医师协会整合医学学分会副会长、上海交通大学女医师女教师协会会长、上海市欧美同学会妇女委员会副主任、中国抗衰老促进会自然抗衰专业委员会副主任、上海市三八红旗手、上海市浦江人才、《General Psychiatry》等刊物编委。

研究方向：精神障碍精准医学及生物机制、冥想科学机制及应用、非药物精准整合干预治疗精神疾病

研究成果：

   近年来开创了基于精准医学检测的非药物整合干预治疗精神疾病的方向。主持国家自然科学基金（5项）、国家重点研发精准医学项目等多项科研项目。在国内首次采用基因芯片筛查精神分裂症易感基因，在国际上发现数个新的精神疾病风险基因及生物标记物，在《Journal of Clinical Investigation》、《Brain》、《Molecular Psychiatry》、《eBiomedicine》等高影响力刊物上发表论文100余篇。授权发明专利4项，主编、参编多部学术专著，主编我国首部从科学角度系统介绍冥想的《冥想科学基础与应用》及国内首部《精神分裂症精准医学临床诊疗指南》《双相障碍精准医学临床诊疗指南》《精神疾病啮齿类动物模型及行为学实验》等专著。

联系方式：
地址：上海市沪闵路3210号科研楼
Email: manyucc@126.com

Donghong Cui:  MD& PhD.

Professor of psychiatry of Shanghai Jiao Tong University School of Medicine and Principal Investigator of the Shanghai Mental Health Center. Shi is the executive director of Shanghai Key Laboratory of Psychotic Disorders, and director of Bio-Bank of mental illness.  She received her Ph.D. from Fudan University, Shanghai. She pursued postdoctoral training in Yale University, USA. She serves as the Standing Committee Member and secretary general of the Chinese Society of Neuroscience& Psychiatry (CSNP), the President of the neuromodulation Union of CSNP, the Standing Committee Member Chinese Research Hospital Association Clinical Data and Biobank Committee; the Executive Committee Member of the Shanghai Society of Genetics, and the Committee Member of China Medicinal Biotech Association Biobank Branch, etc.
Her research has been supported by grants from NSFC, Ministry of Science and Technology of the People’s Republic of China, and Science and Technology Commission Shanghai Municipality etc. She is the PI of National Key R&D Program of China “The multimodal precise medicine on diagnosis and treatment for schizophrenia and biphasic disorder”.
Her research interests focus on Pathogenesis of Schizophrenia, bipolar disorder and other Psychotic disorders; biomarkers and precision medicine of psychotic disorders; Mechanism of metabolic disorders induced by antipsychotic drugs ; Identification of features of speech for diagnosis of manic psychosis. In recent years she also explore mechanism of meditation to promote psychosomatic health
Dr. Cui won several awards, and more than 70 academic papers have been published in journals such as <Molecular Psychiatry>, <Journal of Clinical Investigation> , etc.

代表性论文：

• Pu Z, Huang H, Li M, Li H, Shen X, Wu Q, Ni Q, Lin Y, Cui D.An exploration of distinguishing subjective cognitive decline and mild cognitive impairment based on resting-state prefrontal functional connectivity assessed by functional near-infrared spectroscopy.Front Aging Neurosci. 2025 Jan 8;16:1468246.
• Pu Z, Huang H, Li M, Li H, Shen X, Du L, Wu Q, Fang X, Meng X, Ni Q, Li G, Cui D. Screening tools for subjective cognitive decline and mild cognitive impairment based on task-state prefrontal functional connectivity: a functional near-infrared spectroscopy study. Neuroimage. 2025 Apr 15;310:121130.
• Du L, Huang H, Pu Z, Shi Y, Tong S, Sun J, Cui D.A potential diagnostic biomarker for schizophrenia based on local functional connectivity using dynamic regional phase synchrony. Schizophr Res. 2025 Apr;278:57-64.
• Du L, Jiao X, Shi K, Mo D, Zhou J, Shi Y, Zhang X, Zeng Z, Li H, Duan D, Tong S, Sun J, Cui D.
• Mismatch negativity deficits in schizophrenia and bipolar disorder. J Psychiatr Res. 2025 Aug;188:94-103.
• Pu Z, Wu Y, Zhu Z, Zhao H, Cui D.A new horizon for neuroscience: terahertz biotechnology in brain research.Neural Regen Res. 2025 Feb 1;20(2):309-325.
• Yao S, Wang L, Yang Z, Xu Y, Zhang X, Shi Y, Cui D. Accelerated pace of frailty in patients with schizophrenia.J Nutr Health Aging. 2025 Jan;29(1):100412.
• Xue T, Liu W, Wang L, Shi Y, Hu Y, Yang J, Li G, Huang H, Cui D. Extracellular vesicle biomarkers for complement dysfunction in schizophrenia. Brain. 2024 Mar 1;147(3):1075-1086.
• Xue T, Sheng J, Gao H, Gu Y, Dai J, Yang X, Peng H, Gao H, Lu R, Shen Y, Wang L, Wang L, Shi Y, Li Z, Cui D.Eight-month intensive meditation-based intervention improves refractory hallucinations and delusions and quality of life in male inpatients with schizophrenia: a randomized controlled trial.Psychiatry Clin Neurosci. 2024 Apr;78(4):248-258.
• Xu Y, Yao S, Yang Z, Shi Y, Zhang X, Wang L, Cui D.The Association Between Prolactin Levels and Cognitive Function in Female Patients With Severe Mental Disorders.Psychiatry Investig. 2024 Aug;21(8):832-837.
• Chen X, Gao P, Qi Y, Li Z, Huang H, Shi Y, Wang L, Cui D, Qi D.High circulating MIF levels indicate the association with atypical antipsychotic-induced adverse metabolic effects. Transl Psychiatry. 2024 May 27;14(1):210.
• Chen X, Huang H, Pu Z, Shi Y, Wang L, Yao S, Cui D.Increased risk of atypical antipsychotics-induced metabolic syndrome associated with MIF CATT >5/6 among females with chronic schizophrenia. Schizophr Res. 2024 Aug;270:94-101.
• Chen L, Li L, Cui D, Huang Y, Tong H, Zabihi H, Wang S, Qi Y, Lakowski T, Leng L, Liu S, Wu H, Young LH, Bucala R, Qi D.Extracellular macrophage migration inhibitory factor (MIF) downregulates adipose hormone-sensitive lipase (HSL) and contributes to obesity. Mol Metab. 2024 Jan;79:101834.
• Han Y, Du L, Huang Q, Cui D, Li Y.Enhancing specialization of attention-related EEG power and phase synchronism brain patterns by meditation.Cereb Cortex. 2024 Jul 3;34(7):bhae288.
• Cheng Y, Chen X, Zhang XQ, Ju PJ, Wang WD, Fang Y, Lin GN, Cui DH. Interaction between RNF4 and SART3 is associated with the risk of schizophrenia.Heliyon. 2024 Jun 8;10(12):e32743.
• Qin M, Guan J, Huang Y, Lin H, Cui D, Yao T, Tian C, Wong M, Shi Z, Yuan T.A novel model of drug cue-induced behaviours in rhesus macaque subjected to chronic ketamine exposure. Gen Psychiatr. 2023 Jan 26;36(1):e100902.
• Duan D, Wang L, Feng Y, Hu D, Cui D. Picroside Ⅱ attenuates neuropathic pain by regulating inflammation and spinal excitatory synaptic transmission.Can J Physiol Pharmacol. 2024 Apr 1;102(4):281-292.
• Yang Z, Yao S, Xu Y, Zhang X, Shi Y, Wang L, Cui D. Identification of a Predictive Model for Schizophrenia Based on SNPs in a Chinese Population. Neuropsychiatr Dis Treat. 2024 Aug 9;20:1553-1561.