博士，副研究员，硕士生导师

              博士：2005-2010  上海交通大学生物医学工程专业

              博士后：2014-2015  美国哈佛医学院附属布莱根妇女医院

              Email: yytang0522@gmail.com

 

个人介绍：

上海市精神卫生中心副研究员、硕士生导师，上海交通大学生物医学工程专业博士，哈佛医学院博士后，多次在哈佛医学院、诺丁汉大学访问进修。一作/通讯作者发表SCI论著20篇，代表论著发表在American Journal of Psychiatry, Brain Stimulation等；主持国家自然科学基金(面上、青年)2项、上海市科委临床科技创新行动计划临床医学领域项目、上海市自然科学基金等；获得上海市医疗卫生优秀青年人才培养计划、上海交通大学晨星优秀青年教师等荣誉。

 

研究方向:

1、精神疾病早期的多模态影像学标志物研究；

2、经颅磁刺激等新型神经调控技术的机制及应用研究。

 

代表性项目

1. 国家自然科学基金面上项目，81871050，前额叶-杏仁核网络“可控性”在精神病发病中的作用机制，2019.1-2022.12；

2. 国家自然科学基金青年项目，61102020，抑郁症左右额叶信息交流模式及其在治疗中的应用，2012.1-2014.12;

3. 上海市科学技术委员会“科技创新行动计划”临床医学领域，17411953100，大数据驱动的精准颅外无创神经调控开发及其在精神分裂症早期干预中的应用， 2017.10-2020.9；                                      

4. 上海市自然科学基金，17ZR1424700，经颅磁刺激精准调控抑郁障碍额叶-边缘系统的动态模式及疗效预测，2017.5-2020.4；                                                    

5. 上海市科委医学引导项目，134119b0300，精神病高危综合征早期识别的皮质抑制指标研究， 2013.6-2016.6；                            

6. 上海市卫生和计划生育委员会，201640050，双模态脑影像引导的经颅磁刺激精准治疗抑郁障碍的研究，2017.1-2019.12

 

代表性论文：

1. Tang Y.*, Pasternak O.*,#, Kubicki M., Rathi Y., Zhang T., Wang J., Li H, Woodberry K.A. Xu L., Qian Z., Zhu A., Whitfield-Gabrieli S., Keshavan M.S., Niznikiewicz M., Stone W.S., McCarley R.W., Shenton M.E., Wang J. #, Seidman, L.J., Altered Cellular White Matter but not Extracellular Free-Water in Individuals at Clinical High Risk for Psychosis, the American Journal of Psychiatry, 2019 (IF=13.39，并列一作，已录用)；

2. Wang J*, Tang Y*,#, Curtin A, Xia M, Tang X, Zhao Y, Li Y, Qian Z, Sheng J, Zhang T, Jia Y, Li C, Wang J#., ECT-induced brain plasticity correlates with positive symptom improvement in schizophrenia by voxel-based morphometry analysis of grey matter. Brain stimulation 2019, vol 12: 319-328(IF=6.12，并列一作，共同通讯作者);                                 

3. Zhang T*#., Zhu J.*, Xu L., Tang X., Cui H., Wei Y., Wang Y., Hu Q., Qian Z., Liu X., Tang, Y.#, Li C., Wang J.#, Add-on rTMS for the Acute Treatment of Depressive Symptoms is Probably More Effective in Adolescents than in Adults: Evidence from Real-world Clinical Practice，Brain stimulation 2019, vol 12: 103-109 (IF=6.12，共同通讯作者);

4. Tang Y*, Wang J, Zhang T, Xu L, Qian Z, Cui H, Tang X, Li H, Whitfield-Gabrieli S, Shenton ME, Seidman LJ, McCarley RW, Keshavan MS, Stone WS, Wang J#, Niznikiewicz MA. (2019): P300 as an index of transition to psychosis and of remission: Data from a clinical high risk for psychosis study and review of literature. Schizophr Res. 2019 Feb 25. pii: S0920-9964(19)30074-X(IF=3.9, , 第一作者).                                 

5. Tang Y.*, Ying C., Wang J., Jiao X., Qian Z., Zhang T., Tong S., Sheng J., Sun J.#, Wang J.#,Precise Theta Burst Transcranial Magnetic Stimulation Selectively Reduced Duration-Related Mismatch Negativity, Biological Psychology 2018, vol 137:125-132(IF=2.89);                                                                                                                                   

6.Tang, Y.*, T. Zhang, B. Edelman, B. Zeng, S. Zhao, C. Li, K. Zhuo, Z. Qian, H. Li, Q. Guo, H. Cui, Y. Zhu, L. Jiang, C. Li, D. Yu and J. Wang (2014). "Prolonged cortical silent period among drug-naive subjects at ultra-high risk of psychosis." Schizophr Res 160(1-3): 124-130 (IF=3.96, 第一作者).                                                                                                                

7.Tang, Y.*, X. Zhang, M. Simmonite, H. Li, T. Zhang, Q. Guo, C. Li, Y. Fang, Y. Xu and J. Wang (2013). "Hyperactivity within an extensive cortical distribution associated with excessive sensitivity in error processing in unmedicated depression: a combined event-related potential and sLORETA study." Int J Psychophysiol 90(2): 282-289 （IF=2.87, 第一作者）.                 

8. Wang, J.*, Y. Tang *#, A. Curtin, R. C. K. Chan, Y. Wang, H. Li, T. Zhang, Z. Qian, Q. Guo, Y. Li, X. Liu, X. Tang and J. Wang# (2018). "Abnormal auditory-evoked gamma band oscillations in first-episode schizophrenia during both eye open and eye close states." Prog Neuropsychopharmacol Biol Psychiatry 86: 279-286 (IF=4.19, 并列一作，共同通讯作者).

9. Cao, D., Y. Li, M. A. Niznikiewicz#, Y. Tang# and J. Wang# (2018). "The theta burst transcranial magnetic stimulation over the right PFC affects electroencephalogram oscillation during emotional processing." Prog Neuropsychopharmacol Biol Psychiatry 82: 21-30 (IF=4.19，共同通讯作者).

10. Tang Y.*, Zhang X.*, Sheng J., Zhang X., Zhang J., Xu J., Zhu Y., Wang J., Zhang T., Tong S., Ning L., Liu M., Li Y#, Wang J#. Elevated hippocampal choline level is associated with altered functional connectivity in females with major depressive disorder: A pilot study.Psychiatry Research: Neuroimaging 278 (2018):48-55 (IF=2.46, 并列一作)